1.6 Entropion

Date of last review:

29/4/2026

Date of next review:

29/4/2028

Date of publication:

6/7/2026


Differential Diagnosis (1) 

  • Eyelidretraction (e.g. Graves’ disease) 

    • lashes appear hidden due to retracted lid fold  

  • Distichiasis 

    • extra congenital row of lashes from meibomian gland orifices  

  • Trichiasis 

    • normally positioned lashes misdirected toward the cornea, typically from inflammation  

  • Dermatochalasis 

    • redundant eyelid skin causing misdirected lashes, common in older adults  

  • Epiblepharon  

    • congenital horizontal skin fold causing vertical lash misdirection; often asymptomatic and resolves with age  


Possible management by optometrist  

Advice (1) 

  • Lid taping to the cheek to rotate the lid/lashes away from the globe

    • useful in involutional or spastic entropion  

  • Epilation for localised trichiasis (e.g. cicatricial entropion)  

  • Therapeutic (bandage) contact lens to protect the cornea from lash abrasion  

Treatment 

  • Ocular lubricants for tear deficiency/instability related symptoms (drops for use during the day, unmedicated ointment for use at bedtime)(1). Refer to local formularies for suitable options (6)

NB. Patients with long-term topical medication use may develop sensitivity to preservatives or active ingredients — switch to unpreserved preparations where appropriate (1)


Typical adult dosage/duration

(Blue text = IP, black text = non-IP)

  • As required (see ‘Treatment’ above)  

Regimens should be adjusted according to severity and patient factors (e.g. age, weight, pregnancy, renal function). Prescribing should follow local formulary and national guidance where available (7).  

In cases of known sensitivities, please consult local formularies for alternative options (7)


Further management options (1) 

  • Routine referral after initial optometric management is standard  

  • Urgent referral is required if:  

    • Congenital entropion 

    • Any sight threatening corneal involvement  


Possible management in secondary care or local/community pathways where available (1) 

Surgical Management 

  • Surgery provides definitive treatment for all entropion types; procedure selection depends on underlying cause(s)  

Indications for Surgery 

  • Persistent symptoms 

  • Recurrent bacterial conjunctivitis 

  • Reflex tear hypersecretion 

  • Persistent epiphora 

  • Superficial keratopathy 

  • Risk of ulceration or microbial keratitis  

Evidence Supported Approaches 

  • Combined horizontal and vertical eyelid tightening is effective for involutional entropion  

  • Botulinum toxin injections may provide temporary relief in spastic entropion  


College of Optometrists Clinical Management Guideline (1)  

Entropion - College of Optometrists

* With special thanks to The College of Optometrists for providing the evidence framework for diagnosis and management from the Clinical Management Guidelines (CMGs) for this condition. All references to the College/CMGs are included where appropriate and form the basis of the Community Eyecare Guidelines.


Guidance is informed by the following sources 

  1. College of Optometrists Clinical Management Guidelines Clinical Management Guidelines - College of Optometrists

  2. Advisory alignment with the College of Optometrists Formulary Optometrists' Formulary - College of Optometrists

  3. Advisory alignment with the BNF BNF (British National Formulary) | NICE

  4. Advisory alignment with the Summary Product Characteristics taken from the EMC Home - electronic medicines compendium (emc)

  5. Advisory alignment with Scottish Health Board formularies (where a clear majority is present) *

  6. Advisory alignment with expert consensus (CEGG), informed by sources 2-5 above

  7. Advisory alignment with expert consensus (CEGG) 

  8. “Annex C of the Statement” https://www.eyes.nhs.scot/for-professionals/legislation/

* Scottish formularies should be available within the Prescribing section of your Health Board pages on the eyes.nhs.scot website. If unavailable, contact your local Health Board for further information; Health Boards landing page 

 


If you have a query relating to this page, please email NSS.ComEyecareGuidelineGroup@nhs.scot